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Exactly about Gene Transfer and Genetic Recombination in Bacteria

February 6, 2020 Mexicandate  No comments

Exactly about Gene Transfer and Genetic Recombination in Bacteria

The following points highlight the 3 modes of gene transfer and hereditary recombination in bacteria. The modes are: 1. Transformation 2. Transduction 3. Bacterial Conjugation.

Mode no. 1. Change:

Historically, the finding of change in germs preceded one other two modes of gene transfer. The experiments carried out by Frederick Griffith in 1928 suggested when it comes to first-time that a gene-controlled character, viz. formation of capsule in pneumococci, could possibly be utilized in a non­-capsulated number of these germs. The transformation experiments with pneumococci fundamentally resulted in a discovery that is equally significant genes are constructed with DNA.

In these experiments, Griffith utilized two strains of pneumococci (Streptococcus pneumoniae): one with a polysaccharide capsule creating ‘smooth’ colonies (S-type) on agar dishes that was pathogenic. One other stress had been without capsule creating that is‘rough (R-type) and ended up being non-pathogenic.

If the living that is capsulated (S-bacteria) had been inserted into experimental pets, like laboratory mice, a substantial proportion associated with mice passed away of pneumonia and live S-bacteria could be separated through the autopsied pets.

If the non-capsulated living pneumococci (R-bacteria) were likewise inserted into mice, they stayed unaffected and healthier.

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